Glycolysis causes invasion of glioblastoma cells by increased secretion of cathepsinB
Autor: | Proescholdt, M, Al-Zabin, M, Störr, EM, Lohmeier, A, Brawanski, A |
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Jazyk: | angličtina |
Rok vydání: | 2009 |
Předmět: | |
Zdroj: | 60. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit den Benelux-Ländern und Bulgarien; 20090524-20090527; Münster; DOCP14-01 /20090520/ |
DOI: | 10.3205/09dgnc399 |
Popis: | Objective: Malignant gliomas show high rates of glycolysis caused by hypoxia and specific gene alterations. This leads to high glucose utilization rates combined with increased levels of lactic acid. We hypothesized that hypoxia-inducible carbonic anhydrase (CA) IX is involved in the extrusion of hydrogen[for full text, please go to the a.m. URL] 60. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit den Benelux-Ländern und Bulgarien |
Databáze: | OpenAIRE |
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