Increased incidence of peptic ulcer disease in central serous chorioretinopathy patients: a population-based retrospective cohort study
| Autor: | Yi Chiao Chen, San Ni Chen, Iebin Lian, Jau Der Ho |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Peptic Ulcer Databases Factual Population Taiwan chemical and pharmacologic phenomena Disease Cohort Studies Age Distribution Risk Factors Internal medicine medicine Humans education Retrospective Studies education.field_of_study biology business.industry Proportional hazards model Incidence (epidemiology) Incidence Retrospective cohort study General Medicine Helicobacter pylori Middle Aged biology.organism_classification digestive system diseases Ophthalmology Central Serous Chorioretinopathy Cohort Income Female business Cohort study |
| Zdroj: | Retina (Philadelphia, Pa.). 35(2) |
| ISSN: | 1539-2864 |
| Popis: | Purpose: To investigate peptic ulcer disease and other possible risk factors in patients with central serous chorioretinopathy (CSR) using a population-based database. Methods: In this population-based retrospective cohort study, longitudinal data from the Taiwan National Health Insurance Research Database were analyzed. The study cohort comprised 835 patients with CSR and the control cohort comprised 4175 patients without CSR from January 2000 to December 2009. Conditional logistic regression was applied to examine the association of peptic ulcer disease and other possible risk factors for CSR, and stratified Cox regression models were applied to examine whether patients with CSR have an increased chance of peptic ulcer disease and hypertension development. Results: The identifiable risk factors for CSR included peptic ulcer disease (adjusted odd ratio: 1.39, P = 0.001) and higher monthly income (adjusted odd ratio: 1.30, P = 0.006). Patients with CSR also had a significantly higher chance of developing peptic ulcer disease after the diagnosis of CSR (adjusted odd ratio: 1.43, P = 0.009). Conclusion: Peptic ulcer disease and higher monthly income are independent risk factors for CSR. Whereas, patients with CSR also had increased risk for peptic ulcer development. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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