Vitamin A and vitamin E status of rural preschool children in West Java, Indonesia, and their response to oral doses of vitamin A and of vitamin E
| Autor: | James Allen Olson, A Dedi, H R Bergen, G Natadisastra, H Muhilal, D Karyadi |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Male
Vitamin medicine.medical_specialty medicine.medical_treatment Population Administration Oral Nutritional Status Medicine (miscellaneous) Blood lipids West java chemistry.chemical_compound Oral administration Internal medicine medicine Humans Vitamin E Vitamin A education education.field_of_study Nutrition and Dietetics business.industry medicine.disease Lipids Vitamin A deficiency Endocrinology chemistry Indonesia Child Preschool Female High incidence business |
| Zdroj: | The American Journal of Clinical Nutrition. 48:279-285 |
| ISSN: | 0002-9165 |
| DOI: | 10.1093/ajcn/48.2.279 |
| Popis: | Vitamin A and E status was studied in 5 groups (satisfactory growth reduced growth night blindness Bitots spots and corneal xerosis) of rural Indonesian preschool children. All groups except corneal xerosis showed satisfactory weight-height ratios. Initial serum retinol values were 0.35 micromol/L in 34% of all children. After oral administration of 24.4 micromol vitamin A mean serum retinol values rose from 0.42 to 0.70 micromol/L at 10d. After oral treatment of children with 244 or 314 micromol vitamin A mean serum retinol remained 0.56 micromol/L for 165d. Of particular note were the low mean initial serum alpha-tocopherol concentrations (6.3 micromol/L) and alpha-tocopherol-total lipid ratios (1.5 micromol/g). Total serum lipids fell in the normal range. Oral administration of 84 micromol vitamin E raised serum alpha-tocopherol and alpha-tocopherol-total lipid ratios by 46 and 44% respectively. Thus vitamin E inadequacy which impairs vitamin A absorption and storage may well contribute to the high incidence of clinical vitamin A deficiency in West Javan children. (authors modified) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|