Efficacy and Safety of an Advanced Formula Silicone Gel for Prevention of Post-Operative Scars
| Autor: | Amey Mane, Ganesh Kadhe, Lileswar Kaman, Bikash Medhi, Rakesh K. Sewal |
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| Jazyk: | angličtina |
| Předmět: |
medicine.medical_specialty
integumentary system business.industry Standard treatment Scars Post-operative scar Dermatology medicine.disease Hyperpigmentation Surgery Silicone gel Plastic surgery Keloid Vascularity Hypertrophic medicine Oral and maxillofacial surgery Itching medicine.symptom business Original Research |
| Zdroj: | Dermatology and Therapy |
| ISSN: | 2193-8210 |
| DOI: | 10.1007/s13555-013-0036-8 |
| Popis: | Introduction Scar formation is a natural part of the healing process that occurs when the skin repairs wounds caused by burns, trauma, surgery or disease. The appearance of scars often leads to adverse psychological effects, loss of self-esteem and the associated stigmatism and diminished quality of life. Silicones are emerging as the standard treatment for prevention of a wide range of scars. The present study evaluated the safety and efficacy of an advanced formula topical silicone gel for prevention of post-operative hypertrophic and keloid scars. Methods An open-label prospective trial was conducted. Patients who had undergone prior surgery (10 days–3 weeks) and having recent post-surgical scars were enrolled. Patients were asked to apply the gel twice daily to the affected areas for 3 months. Pigmentation, vascularity, pliability, height of scar and pain and pruritus in the scar were assessed. Photographs of scars were taken before commencement of treatment and at follow-up visits. Results A total of 36 patients were enrolled. At baseline, height of the scar was 2–5 mm in 57.6 % (19/33) of the subjects which was reduced in subsequent visits (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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