Effect of 24-hour blood pressure and heart rate variations on left ventricular hypertrophy and dilatation in essential hypertension
Autor: | Serafim Nanas, John A. Papadakis, Helen Psihogios, Savvas Toumanidis, Dimitra S. Moulopoulos, Stamatios F. Stamatelopoulos, John Kanakakis, Spyridon D. Moulopoulos, Nikolaos Zakopoulos |
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Rok vydání: | 1990 |
Předmět: |
Adult
Male medicine.medical_specialty Cardiomegaly Essential hypertension Left ventricular hypertrophy Muscle hypertrophy Heart Rate Internal medicine Heart rate Humans Medicine cardiovascular diseases Interventricular septum Monitoring Physiologic medicine.diagnostic_test business.industry Middle Aged medicine.disease medicine.anatomical_structure Blood pressure Echocardiography Hypertension Multivariate Analysis Ambulatory Electrocardiography Ambulatory Cardiology Female Radiography Thoracic Cardiology and Cardiovascular Medicine business Electrocardiography Dilatation Pathologic |
Zdroj: | American Heart Journal. 119:1147-1152 |
ISSN: | 0002-8703 |
DOI: | 10.1016/s0002-8703(05)80246-7 |
Popis: | This study correlates variables derived from blood pressure (BP) and heart rate (HR) monitoring with the degree of left ventricular structural changes in essential hypertension. Forty patients with mild-to-moderate hypertension according to World Health Organization criteria underwent 24-hour ambulatory monitoring. Echocardiographic (posterior wall and interventricular septum thickness, left ventricular mass) or ECG (SV1 + RV5) indices of hypertrophy were significantly (p less than 0.01) correlated (positive correlations) with derivatives of BP monitoring (mean systolic and diastolic BP values) but not with HR derivatives. Echocardiographic indices of dilatation (left ventricular end-diastolic volume and diameter) were significantly (p less than 0.01 to less than 0.001) correlated (negative correlations) with derivatives of HR monitoring (mean HR values, mainly during the night) but not with BP derivatives. It is concluded that in essential hypertension, left ventricular hypertrophy depends on mean 24-hour systolic and diastolic BP values, whereas left ventricular dilatation appears to be more prominent in patients with bradycardia mainly during the night. |
Databáze: | OpenAIRE |
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