Moisturizing and antioxidant evaluation of Moringa oleifera leaf extract in topical formulations by biophysical techniques
| Autor: | Perla Giovanna Silva-Flores, Sergio Arturo Galindo-Rodríguez, Ariana A. Huerta-Heredia, Rocío Álvarez-Román, Wagner Vilegas, David Paniagua-Vega |
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| Přispěvatelé: | Universidad Autónoma de Nuevo León, Instituto de Biotecnología. Universidad del Papaloapan, Universidade Estadual Paulista (Unesp), Cátedras CONACYT-UANL, Cátedras CONACYT-UNPA |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
Antioxidant medicine.medical_treatment Plant Science Antioxidant potential 01 natural sciences ESI-IT-MSn Moringa Lipid peroxidation chemistry.chemical_compound medicine Food science Moringa oleífera Gel Chemistry Skin bioengineering techniques Moringa oleifera leaf extract 0104 chemical sciences Hydroalcoholic extract 010404 medicinal & biomolecular chemistry Phytochemical Protected cropping Drug delivery Nanoparticles SPE Ferric thiocyanate 010606 plant biology & botany |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| Popis: | Made available in DSpace on 2020-12-12T01:48:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-03-01 Consejo Nacional de Ciencia y Tecnología The phytochemical profile, formulations (nanoparticles and gel), moisturizing and antioxidant potential of a hydroalcoholic fraction of Moringa oleifera leaves (HFM) were determined. These were obtained through the application of eco-friendly strategies of cultivation and processing. The HFM phytochemical analysis by ESI-IT-MSn showed the presence of seven compounds (flavonoids and phenolic acids). The viscosity, pH and particle size of HFM formulations ensure the suitability for topical application. Antioxidant activity was determined by inhibition of lipid peroxidation and ferric thiocyanate in vitro; it was confirmed that HFM and in formulations showed a significant inhibition of oxidation. In relation to the in vitro skin biophysical evaluation for topical formulations of HFM, water content, lipids and trans-epidermal water loss on the skin were favored with the presence of HFM. In addition, skin pH was not been modified. Our results emphasize the moisturizing and antioxidant potential of the moringa-formulation as a new skin drug delivery system. Departamento de Química Analítica Facultad de Medicina Universidad Autónoma de Nuevo León, Av. Fco. I. Madero y Dr. E. Aguirre Pequeño s/n Departamento de Química Analítica Facultad de Ciencias Biológicas Universidad Autónoma de Nuevo León, Av. Pedro de Alba s/n Instituto de Biotecnología. Universidad del Papaloapan, Av. Circuito Central No. 200 Col. Parque Industrial. Tuxtepec Instituto de Biociências – Câmpus do litoral Paulista UNESP – Universidade Estadual Paulista, Praça Dom Infante Henrique s/n, Parque Bitaru CEP 11330-900, São Vicente Cátedras CONACYT-UANL Cátedras CONACYT-UNPA Instituto de Biociências – Câmpus do litoral Paulista UNESP – Universidade Estadual Paulista, Praça Dom Infante Henrique s/n, Parque Bitaru CEP 11330-900, São Vicente Consejo Nacional de Ciencia y Tecnología: - Consejo Nacional de Ciencia y Tecnología: 284813 Consejo Nacional de Ciencia y Tecnología: CB/2016 |
| Databáze: | OpenAIRE |
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