Neuropsychological Deficits Associated with Destruction of the Right Nigrostriatal Pathway
| Autor: | Francisco Escamilla-Sevilla, Josefina Martínez-Simón, Adolfo Mínguez-Castellanos, Marisa Arnedo, C. Sáez-Zea |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Nigrostriatal pathway Substantia nigra Neuropsychological Tests Functional Laterality Lesion Parkinsonian Disorders Visual memory Neural Pathways Humans Medicine Neurologic Examination Tomography Emission-Computed Single-Photon Denervation business.industry General Neuroscience Dopaminergic Neuropsychology Cognition Iofetamine Corpus Striatum Substantia Nigra Psychiatry and Mental health Clinical Psychology medicine.anatomical_structure Neurology (clinical) Radiopharmaceuticals medicine.symptom Cognition Disorders business Neuroscience |
| Zdroj: | Journal of the International Neuropsychological Society. 19:729-734 |
| ISSN: | 1469-7661 1355-6177 |
| Popis: | Hemiparkinsonism secondary to a vascular mesencephalic lesion is infrequent; these patients offer an exceptional opportunity to study neuropsychological alterations attributable to unilateral dopaminergic denervation, shedding light on the pathophysiology of cognitive disorders in early-stage idiopathic Parkinson's disease (PD). From the investigation of our case, we conclude that destruction of the right nigrostriatal pathway is accompanied by deficits in executive functioning and verbal/visual memory similar to those observed in many patients with early-stage idiopathic PD. The more complex neuropsychological dysfunction developed by other PD patients must therefore be related to the additional involvement of other brain structures. (JINS, 2013, 19, 1–6) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|