Testicular mixed germ cell tumour with isolated skip metastasis to unilateral pleura: First case reported in the literature

Autor: Manmohan Kamat, Neeraj Pratap Singh, Shravani Shetye, Kartik Nattey, Seema Barman
Rok vydání: 2019
Předmět:
Zdroj: International Journal of Surgery Case Reports
ISSN: 2210-2612
Popis: Highlights • Mixed germ cell tumour with skip metastasis to unilateral pleura without involvement of any retroperitoneal lymph nodes or secondary to hematogenous spread involving mediastinal structures or any other distant sites is extremely rare. • Histological subtype of metastatic lesion is different from the histological subtype of the primary tumour. • Changing nature of histology of tumour with chemotherapy and progress of disease. • Combined approach of chemotherapy and surgery is needed in case of mixed germ cell tumour depending on the histological subtype, metastasis and clinical presentation of the patient.
Introduction Testicular germ cell tumours metastasize in a very predictable fashion involving the retroperitoneal lymph nodes first followed by either lymphatic spread via thoracic duct or hematogenous spread to distant organs like lungs, liver and brain. Presentation of case We encountered a case of 21-year-old gentleman with mixed germ cell tumour of testis who later presented with respiratory complaints which turned out to be a metastatic differentiated teratoma of unilateral pleura without involvement of retroperitoneal lymph nodes or any other organs. Discussion Skip Metastasis to unilateral pleura is an extremely rare entity for testicular mixed germ cell tumour and no case has been reported in the literature so far.
Databáze: OpenAIRE