| Autor: |
S. Martella, C. Bauco, G. Zannino, Vincenzo Marigliano, A.M. Cinti, C. Borriello, C. Rossetti, Mauro Cacciafesta |
| Předmět: |
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| Zdroj: |
Scopus-Elsevier |
| Popis: |
Summary According to numerous investigations, age and education are in correlation with mini-mental state examination (MMSE) scores. However, several of the studies are based on cohorts not including elderly over 90 years of age. We assessed both the independent and joint effects of these factors on MMSE performance in a group of 101 Italian centenarians with the aim of better understanding how age and years of schooling are associated with changes of cognitive status in the longest living patients. Our data demonstrate that the distribution of the MMSE has a wide range in centenarians: mean score was 18.7 ± 7.4 and 43 % of them were included within the normal or borderline area. There were not significant differences by sex. As expected, there is an increase in the prevalence of cognitive impairment as educational level decreases. A cutoff point of 6 years of schooling has emerged as discriminant for a two level distribution of MMSE scores. While the general population scores progressively increase with the passage from one lower category of schooling to the next, centenarians show a single level of increase which entirely accounts for the differences between subjects. Furthermore, centenarians with lower educational level are at higher risk for cognitive deterioration prior to death. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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