Self-reported lack of energy or feeling depressed 12 months after treatment in men diagnosed with prostate cancer within a population-based registry
| Autor: | Ian D. Davis, Nathan Lawrentschuk, Lachlan Dodds, Haryana M. Dhillon, Melanie Evans, Mark Frydenberg, Jonathan G Bensley, Nathan Papa, Damien M Bolton, Sue M Evans, Paul Kearns, Declan G. Murphy, Jeremy Millar |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty media_common.quotation_subject Population Emotions Experimental and Cognitive Psychology Androgen deprivation therapy Prostate cancer Quality of life Internal medicine medicine Humans Prospective Studies Registries education Depression (differential diagnoses) media_common Aged Prostatectomy education.field_of_study business.industry Prostatic Neoplasms Androgen Antagonists medicine.disease Psychiatry and Mental health Oncology Feeling Quality of Life Anxiety Self Report medicine.symptom Sexual function business |
| Zdroj: | Psycho-oncologyReferences. 31(3) |
| ISSN: | 1099-1611 |
| Popis: | OBJECTIVE: Feeling depressed and lethargic are common side effects of prostate cancer (PCa) and its treatments. We examined the incidence and severity of feeling depressed and lack of energy in patients in a population based PCa registry. METHODS: We included men diagnosed with PCa between 2015 and 2019 in Victoria, Australia, and enrolled in the Prostate Cancer Outcomes Registry. The primary outcome measures were responses to two questions on the Expanded Prostate Cancer Index Composite (EPIC-26) patient reported instrument: problems with feeling depressed and problems with lack of energy 12 months following treatment. We evaluated associations between these and age, cancer risk category, treatment type, and urinary, bowel, and sexual function. RESULTS: Both outcome questions were answered by 9712 out of 12,628 (77%) men. 981 patients (10%) reported at least moderate problems with feeling depressed; 1563 (16%) had at least moderate problems with lack of energy and 586 (6.0%) with both. Younger men reported feeling depressed more frequently than older men. Lack of energy was more common for treatments that included androgen deprivation therapy than not (moderate/big problems: 31% vs. 13%), irrespective of disease risk category. Both outcomes were associated with poorer urinary, bowel, and sexual functional domain scores. CONCLUSIONS: Self-reported depressive feelings and lack of energy were frequent in this population-based registry. Problems with feeling depressed were more common in younger men and lack of energy more common in men having hormonal treatment. Clinicians should be aware of the incidence of these symptoms in these at-risk groups and be able to screen for them. |
| Databáze: | OpenAIRE |
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