Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?
| Autor: | Hasan Biçer, Ayse Saatci Yasar, Hatice Duygu Çiftçi Sivri, Mehmet Bilge, Sina Ali, Yakup Alsancak, Serkan Sivri |
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| Rok vydání: | 2017 |
| Předmět: |
Gynecology
lcsh:Diseases of the circulatory (Cardiovascular) system medicine.medical_specialty business.industry Cholesterol Monocyte lcsh:R Saphenous vein graft lcsh:Medicine Stable angina saphenous vein graft disease chemistry.chemical_compound High-density lipoprotein medicine.anatomical_structure chemistry high-density lipoprotein cholesterol lcsh:RC666-701 Internal medicine Monocyte count medicine Cardiology In patient atherosclerosis business |
| Zdroj: | Koşuyolu Heart Journal, Vol 20, Iss 1, Pp 7-12 (2017) |
| ISSN: | 2149-2980 2149-2972 |
| DOI: | 10.5578/khj.25275 |
| Popis: | Introduction: Circulating monocyte count is a predictive factor of new atherosclerotic plaque development. In addition, there is a strong inverse relationship between high-density lipoprotein (HDL) cholesterol and atherosclerosis. It has been shown that the monocyte/HDL cholesterol ratio (MHR) is a novel inflammatory marker. We aimed to investigate the relationship between MHR and saphenous vein graft disease (SVGD). Patients and Methods: A total of 3 69 patients were divided into 3 groups (positive SVGD group= 150, negative SVGD group= 89, normal coronary artery group= 130). Baseline characteristics and laboratory parameters were recorded and compared among the groups. Results: There were no significant differences between the positive and negative SVGD groups, except for age of SVG and left ventricular ejection fraction, according to baseline characteristics. C-reactive protein (CRP) levels, fasting blood glucose levels and mean platelet volume were higher in the positive SVGD group than in the negative SVGD group (p= 0.008, 0.048 and 0.042, respectively). MHR was not significantly different between the positive and negative SVGD groups (p= 0.169) and normal coronary artery group (p= 0.364). CRP was found to be an independent predictor factor of SVGD. Conclusion: There was no association between MHR and coronary atherosclerosis. MHR was not a predictive factor of SVGD. |
| Databáze: | OpenAIRE |
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