Feasibility and Outcomes of Left Main to Branch Vessel PCI with Novel Tapered Coronary Stent in a Tertiary Care Centre: A Real World Experience
| Autor: | C.N. Manjunath, Rahul Patil, H.S. Natraj Setty, Jayashree Kharge, V A. Sathwik Raj, T.R. Raghu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Coronary Artery Disease Tertiary Care Centers Coronary artery disease Percutaneous Coronary Intervention Risk Factors Coronary stent medicine Humans Cumulative incidence Prospective Studies cardiovascular diseases Pharmacology business.industry Stent Percutaneous coronary intervention Drug-Eluting Stents Hematology General Medicine Middle Aged medicine.disease Surgery Treatment Outcome Conventional PCI Feasibility Studies Molecular Medicine Stents Cardiology and Cardiovascular Medicine business Mace TIMI |
| Zdroj: | Cardiovascular & Hematological Disorders-Drug Targets. 21:128-135 |
| ISSN: | 1871-529X |
| DOI: | 10.2174/1871529x21666210812110944 |
| Popis: | Objective: To assess the safety and efficacy of Novel tapered (BioMime™ Morph) sirolimus- eluting stent (SES) for left main PCI in a real-world scenario. Background: Currently, no data is available on clinical usefulness of tapered ultrathin stents in left main PCI. Methods: This was a prospective, non-randomised, single centre study carried out between February 2018 and May 2020 at a tertiary cardiac care centre in southern India. The study included patients treated with BioMime Morph tapered stent for distal de novo LMB lesion or ostial LAD/LCX lesions with significant size disparity between reference segments based on the eligibility criteria. Primary endpoint of the study was the cumulative incidence of major adverse cardiovascular events (MACE) composed of cardiac death, myocardial infarction, and clinically driven target-lesion revascularisation at follow-up. Results: A total of 41 patients (average age of 54.83±9.81 years) were included in the study. Average SS-2 score was 23.17±5.42. Majority of the lesions (n=31; 75.61%) were of medina class (0.1.0). Provisional single stent strategy was adopted for treatment of LMB lesions. TIMI flow-3 was achieved in 40 patients (97.56%). Median clinical follow-up was 20 months (range 6-34 months). There was no periprocedural complication or MACE during follow-up. Conclusion: Tapered stents may be an acceptable alternative for LM intervention in an anatomical subset of patients with tapered vessels. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|