Severe Fatal Systemic Embolism Due to Non-Bacterial Thrombotic Endocarditis as the Initial Manifestation of Gastric Adenocarcinoma: Case Report
Autor: | Rodica Balasa, Smaranda Maier, Zoltan Bajko, Anita Gothard, Anca Moţăţăianu |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
Context (language use) Case Report 030204 cardiovascular system & hematology Nonbacterial thrombotic endocarditis Gastroenterology 03 medical and health sciences Gastric adenocarcinoma 0302 clinical medicine Internal medicine Cancer screening medicine Endocarditis Stroke business.industry RC86-88.9 Cancer Medical emergencies. Critical care. Intensive care. First aid General Medicine multi-organ arterial infarctions medicine.disease stroke endocarditis gastric adenocarcinoma business Complication 030217 neurology & neurosurgery |
Zdroj: | The Journal of Critical Care Medicine, Vol 4, Iss 2, Pp 68-73 (2018) The Journal of Critical Care Medicine |
ISSN: | 2393-1817 |
Popis: | Introduction Nonbacterial thrombotic endocarditis (NBTE), also known as marantic endocarditis, is a rare, underdiagnosed complication of cancer, in the context of a hypercoagulable state. NBTE represents a serious complication due to the high risk of embolisation from the sterile cardiac vegetations. If these are not properly diagnosed and treated, infarctions in multiple arterial territories may occur. Case presentation The case of a 47-year-old male is described. The patient was diagnosed with a gastric adenocarcinoma, in which the first clinical manifestation was NBTE. Subsequently, a hypercoagulability syndrome was associated with multi-organ infarctions, including stroke and eventually resulted in a fatal outcome. Conclusions NBTE must be considered in patients with multiple arterial infarcts with no cardiovascular risk factors, in the absence of an infectious syndrome and negative blood cultures. Cancer screening must be performed to detect the cause of the prothrombotic state. |
Databáze: | OpenAIRE |
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