Patterning with clocks and genetic cascades: Segmentation and regionalization of vertebrate versus insect body plans
| Autor: | Ezzat El-Sherif, Olivier Pourquié, Margarete Diaz-Cuadros |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Cancer Research
Insecta Gene Expression Review Insect QH426-470 Beetles Morphogenesis Segmentation Molecular clock Lateral root formation Genetics (clinical) media_common Regulation of gene expression Tribolium biology Drosophila Melanogaster Eukaryota Gene Expression Regulation Developmental Vertebrate Animal Models Insects Experimental Organism Systems Vertebrates Genetic Oscillators Drosophila Drosophila melanogaster Arthropoda media_common.quotation_subject Embryonic Development Research and Analysis Methods Model Organisms ddc:570 biology.animal Genetics Animals Humans Gene Regulation Molecular Biology Ecology Evolution Behavior and Systematics Body Patterning Phylum fungi Organisms Biology and Life Sciences Morphogenic Segmentation biology.organism_classification Invertebrates Evolutionary biology Animal Studies Zoology Entomology Developmental Biology |
| Zdroj: | PLoS Genetics, Vol 17, Iss 10, p e1009812 (2021) PLoS Genetics |
| ISSN: | 1553-7404 1553-7390 |
| Popis: | Oscillatory and sequential processes have been implicated in the spatial patterning of many embryonic tissues. For example, molecular clocks delimit segmental boundaries in vertebrates and insects and mediate lateral root formation in plants, whereas sequential gene activities are involved in the specification of regional identities of insect neuroblasts, vertebrate neural tube, vertebrate limb, and insect and vertebrate body axes. These processes take place in various tissues and organisms, and, hence, raise the question of what common themes and strategies they share. In this article, we review 2 processes that rely on the spatial regulation of periodic and sequential gene activities: segmentation and regionalization of the anterior–posterior (AP) axis of animal body plans. We study these processes in species that belong to 2 different phyla: vertebrates and insects. By contrasting 2 different processes (segmentation and regionalization) in species that belong to 2 distantly related phyla (arthropods and vertebrates), we elucidate the deep logic of patterning by oscillatory and sequential gene activities. Furthermore, in some of these organisms (e.g., the fruit fly Drosophila), a mode of AP patterning has evolved that seems not to overtly rely on oscillations or sequential gene activities, providing an opportunity to study the evolution of pattern formation mechanisms. |
| Databáze: | OpenAIRE |
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