The efficacy of linked color imaging for the endoscopic diagnosis of mucosal healing in quiescent ulcerative colitis
| Autor: | Mariko Kajiwara-Kubota, Kazuhiro Kamada, Osamu Dohi, Makoto Tanaka, Yuma Hotta, Ken Inoue, Takeshi Ishikawa, Yuki Toyokawa, Yoshito Itoh, Hideyuki Konishi, Tomohisa Takagi, Kazuhiko Uchiyama, Yuji Naito, Naohisa Yoshida, Mitsuo Kishimoto, Saori Kashiwagi, Nobuaki Yagi |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Statistical difference Severity of Illness Index Gastroenterology 03 medical and health sciences 0302 clinical medicine Recurrence Internal medicine Humans Medicine In patient Intestinal Mucosa Colitis Hepatology business.industry Histology Colonoscopy medicine.disease Ulcerative colitis Colonic mucosa 030220 oncology & carcinogenesis Mucosal healing Colitis Ulcerative 030211 gastroenterology & hepatology Color imaging business |
| Zdroj: | Journal of Gastroenterology and Hepatology. 36:2448-2454 |
| ISSN: | 1440-1746 0815-9319 |
| DOI: | 10.1111/jgh.15489 |
| Popis: | Background and aim The Mayo Endoscopic Subscore (MES) and the Ulcerative Colitis Endoscopic Index of Severity (UCEIS) are used to assess endoscopic mucosal healing in patients suffering from ulcerative colitis. Although mucosal healing is defined by MES 0, relapse of ulcerative colitis is often observed. Over a 48-month period, this study investigated the efficacy of linked color imaging (LCI) in predicting the long-term prognosis of ulcerative colitis patients diagnosed with MES 0. Methods Overall, 26 patients in ulcerative colitis remission, diagnosed with MES 0, were enrolled. Using a LASEREO endoscopic system (Fujifilm Co., Tokyo, Japan), endoscopic colonic images were assessed with linked color imaging and the colitis endoscopic index of severity. Endoscopic LCI images were separated into three subgroups (A, no redness; B, redness with visible vessels; and C, redness without visible vessels). The Geboes score was used to evaluate histology; active mucosa was defined as GS > 2B.1. Results Linked color imaging classification subdivided colonic mucosa, which had been diagnosed with MES 0, into two classes. The LCI-A group did not relapse, and the non-relapse rate was significantly higher (P = 0.018) than that in the LCI-B group. No difference in relapse rates was observed between patients with a colitis endoscopic index of severity of 0 and 1 (P = 0.655). There was no statistical difference between the composition of LCI-A group and the relapse rate between active and inactive mucosa diagnosed by Geboes score. Conclusions This methodology can be used to evaluate mucosal healing and predict long-term outcomes in ulcerative colitis patients. |
| Databáze: | OpenAIRE |
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