1-Benzyloxy-5-phenyltetrazole derivatives highly active against androgen receptor-dependent prostate cancer cells

Autor:	Shiting Zhao, Abdelsalam S. Ali, Xinyu Kong, Yan Zhang, Xiaomin Liu, Melissa A. Skidmore, Craig M. Forsyth, G. Paul Savage, Donghai Wu, Yong Xu, Craig L. Francis
Rok vydání:	2022
Předmět:	Pharmacology Organic Chemistry Drug Discovery General Medicine
Zdroj:	European journal of medicinal chemistry. 246
ISSN:	1768-3254
Popis:	A series of 1-benzyloxy-5-phenyltetrazole derivatives and similar compounds were synthesized and evaluated for their in vitro inhibitory activity against androgen-receptor-dependent (22Rv1) and androgen-receptor independent (PC3) prostate cancer cells. The most active compounds had in vitro IC
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37d60220010735cbbaeb72a476809cc https://pubmed.ncbi.nlm.nih.gov/36495632 Zobrazit plný text záznamu Full Text from ScienceDirect