Assessment of Fluid-Responsiveness Parameters for Off-Pump Coronary Artery Bypass Surgery: A Comparison Among LiDCO, Transesophageal Echochardiography, and Pulmonary Artery Catheter
| Autor: | Gennaro Ismeno, Antonio Pisano, Giovanni De Martino, Maria Rosario Piccirillo, Armando Natale, Luigi Piazza, Luigi Belloni |
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| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Coronary Artery Bypass Off-Pump Internal medicine Intravascular volume status medicine Humans Prospective Studies Pulmonary Wedge Pressure Pulmonary wedge pressure Aged Off-pump coronary artery bypass Blood Volume business.industry Central venous pressure Pulmonary artery catheter Stroke volume Middle Aged Pulse pressure Surgery Anesthesiology and Pain Medicine Blood pressure Catheterization Swan-Ganz Cardiology Fluid Therapy Female Cardiology and Cardiovascular Medicine business Echocardiography Transesophageal |
| Zdroj: | Journal of Cardiothoracic and Vascular Anesthesia. 22:243-248 |
| ISSN: | 1053-0770 |
| Popis: | Objective: To verify the reliability of different markers of fluid-responsiveness during off-pump cardiac surgery (OPCAB). Design: A clinical prospective, nonblinded, nonrandomized study. Setting: A community hospital. Participants: Nineteen patients. Interventions: Pulmonary artery catheter (PAC), LiDCO (LiDCO, London, UK), and transesophageal echocardiography (TEE) parameters were measured before (t0) and after (t1) a fluid challenge was performed 20 minutes after induction of anesthesia, but before sternotomy and without inotropic infusion. A Student t test and Spearman test were performed for statistical analysis. Measurements and Main Results: According to the variation of cardiac index after the fluid challenge (ΔCI%), 2 groups of patients were identified: the responders (Re, ΔCI% > 15%) and the nonresponders (nRe). Mean pulse pressure variation (PPV) and mean stroke volume variation (SVV) before the fluid challenge (t0) were significantly different between the 2 groups. No significant differences were shown in systolic pressure variation (SPV), left ventricular end-diastolic area, left ventricular end-diastolic volume, and peak changes of aortic flow (ΔVAo). A statistically significant correlation was observed between ΔCI% and PPV ( R = 0.793), ΔCI% and SVV ( R = 0.809), and ΔCI% and SPV ( R = 0.766). No correlation with central venous pressure and pulmonary capillary wedge pressure was found. Conclusions: Dynamic parameters of fluid responsiveness by LiDCO are highly sensitive for assessment of intravascular volume status during OPCAB surgery. In contrast, even if static parameters by TEE reflect changes in ventricular diastolic volume, they are poor indicators of fluid responsiveness. Surprisingly, no significant correlation between ΔVAo (TEE) and ΔCI% was found. |
| Databáze: | OpenAIRE |
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