Predictive Value of Preoperative Sarcopenia in Patients with Gastric Cancer: a Meta-analysis and Systematic Review

Autor: Ya-nan Xing, Zhengdao Yang, Bin Ma, Zhenning Wang, Xue Jiang, Xin Zhou
Rok vydání: 2018
Předmět:
Zdroj: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 22(11)
ISSN: 1873-4626
Popis: The impact of preoperative sarcopenia on postoperative complications and overall survival has been recently debated. Our meta-analysis aims to ascertain whether preoperative sarcopenia increases the risk of poor outcomes and to attempt to provide new ideas for the prognosis of outcomes for patients with gastric cancer. We searched for all relevant articles on PubMed, the EMBASE database, and Web of Science (up to September 1, 2017). Data synthesis and statistical analysis were carried out using RevMan 5.3 software. Thirteen studies involving 4262 patients who underwent gastrectomy for gastric cancer were analyzed (sarcopenia group = 1234; non-sarcopenia group = 3028). The results showed that preoperative sarcopenia significantly associated with poor pathological staging (high pT: OR = 1.86, 95% CI = 1.49–2.31; P
Databáze: OpenAIRE