Survival Function and Protein Malnutrition in Burns Patients at a Rural Hospital in Africa

Autor: Benjamin Longo-Mbenza, E. L. Mazwai, A. Dhaffala, H. J. Kingu
Rok vydání: 2011
Předmět:
Zdroj: World Journal of Surgery. 35:1546-1552
ISSN: 1432-2323
0364-2313
DOI: 10.1007/s00268-011-1122-7
Popis: The aim of this study was to estimate the incidence of acute malnutrition and to identify predictors of case fatality among burn patients in the poorest South African province, Eastern Cape. This longitudinal follow-up study was conducted among consecutive burn patients admitted to Nelson Mandela Academic Hospital, Mthatha, South Africa, between 2006 and 2008. Patients were monitored and treated daily from admission to discharge. Outcomes were acute protein malnutrition and mortality. Patients’ demography, total body surface area (TBSA) of the burn, cause of the burn, weight, height, location of the burn, hemoglobin, serum albumin, wound infection, and antibiotics after culture and sensitivity results were the potential predictors of in-hospital mortality. A Cox’s proportional hazards model for the time to death was then used to identify independent predictors of mortality after adjusting for confounding factors. Kaplan–Meier survival curves were generated for each arm of exposure status. In all, 67 patients (35 males, 59 children) were studied. The mean (range) age was 8 ± 12 years (1 month to 59 years). The cumulative incidence of acute malnutrition was 62.0% (n = 42): 46.3% (n = 31) at admission and 15.7% (n = 11) after 7 days of hospitalization. Incidence of mortality was 16.4% (n = 11 with in-hospital acute malnutrition). The only significant and independent predictors of mortality were total body surface area (TBSA) burn >40% [hazard ratio (HR) 10.5, 95% confidence interval (CI) 1.7–63; P
Databáze: OpenAIRE
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