Prevalence and factors associated with common mental disorders in young people living with HIV in sub-Saharan Africa: a systematic review

Autor: Carophine Nasambu, Amina Abubakar, Pim Cuijpers, Charles R. Newton, Ezra K Too, Moses K. Nyongesa, Hans M. Koot
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Adult
medicine.medical_specialty
SDG 16 - Peace
Adolescent
Social Stigma
Psychological intervention
HIV Infections
Review
young people
03 medical and health sciences
Social support
0302 clinical medicine
Acquired immunodeficiency syndrome (AIDS)
SDG 3 - Good Health and Well-being
medicine
Prevalence
Humans
030212 general & internal medicine
Psychiatry
Africa South of the Sahara
Aged
030505 public health
business.industry
Mental Disorders
SDG 16 - Peace
Justice and Strong Institutions

Public Health
Environmental and Occupational Health

correlates
Supplement: Review
medicine.disease
anxiety
Justice and Strong Institutions
Infectious Diseases
Systematic review
Sexual abuse
depression
Anxiety
Female
medicine.symptom
0305 other medical science
business
Psychosocial
Anxiety disorder
sub‐Saharan Africa
Zdroj: Journal of the International AIDS Society
Too, E K, Abubakar, A, Nasambu, C, Koot, H M, Cuijpers, P, Newton, C R J C & Nyongesa, M K 2021, ' Prevalence and factors associated with common mental disorders in young people living with HIV in sub-Saharan Africa : a systematic review ', Journal of the international aids society, vol. 24, no. S2, e25705 . https://doi.org/10.1002/jia2.25705
Popis: © 2021 The Authors. Journal of the International AIDS Society published by John Wiley & Sons Ltd on behalf of International AIDS SocietyIntroduction: Common mental disorders (CMDs) particularly depression and anxiety, are highly comorbid with HIV also in young people living with HIV (YLWH). In sub-Saharan Africa (SSA) where most YLWH reside, there are limited summary data on CMDs among these youths, yet there are previous systematic reviews summarizing data on CMDs among adults living with HIV. We conducted a systematic literature review on the prevalence and correlates of CMDs among YLWH, aged 10 to 24 years, from SSA. Methods: We searched African Index Medicus, African Journals Online and five other electronic databases (from database inception up to 31 December 2020) for relevant studies published in English. The key search terms applied were as follows: “Depression OR Anxiety”, “Young people”, “HIV infections” and “sub-Saharan Africa”. Results and discussion: Out of 3989 articles, 31 studies were included in the review. The prevalence of CMDs in YLWH widely varied ranging between 16.0% and 40.8% for major depression, 4.4% and 52.6% for depressive symptoms and 2.2% and 25.0% for anxiety symptoms. Anxiety disorder was estimated at 45.6%. Four of the five included studies with a comparison group of HIV-negative young people reported significantly higher prevalence estimates of depressive disorders among YLWH. Several sociodemographic, psychosocial and HIV-related correlates of CMDs were reported but most lacked consensus across studies. Nevertheless, female sex, older age, fewer schooling years, HIV-positive status, bullying, sexual abuse, HIV-related stigma, social support and poor antiretroviral therapy adherence were frequently reported (in ≥2 studies) as significant correlates of depressive symptoms among YLWH. Higher social support was the only frequent significant correlate of anxiety symptoms. Conclusions: The burden of CMDs among YLWH from SSA is substantial and appears to be significantly higher when compared with HIV-negative peers, particularly for depressive disorders. However, more comparative research is needed. Importantly, screening for CMDs at the youth HIV-clinics should be prioritized especially for YLWH at high risk of CMDs, to facilitate early management or referral for treatment. Furthermore, youth-friendly psychological interventions addressing CMDs in YLWH should urgently be piloted in SSA, incorporating contextual components that may directly or indirectly reduce symptoms of CMDs among YLWH, such as social support.
Databáze: OpenAIRE