| Autor: |
Julia Merkle-Storms, Christopher Gaisendrees, Manuel Feisst, Bartosz Rylski, Daniel-Sebastian Dohle, Christian Hagl, Mario Lescan, Jens Brickwede, Jochen Poeling, Tomas Holubec, Christian D Etz, Philipp Jawny, Thilo Noack, Rawa Arif, Thorsten Wahlers, Andreas Boening, Maximilian Luehr |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Popis: |
Objectives Age-related atherosclerosis has been shown to cause aortic stiffness and wall rigidification. This analysis aimed to correlate age and dissection extension length in a large contemporary multi-centre study. We hypothesize that younger patients suffer more extensive DeBakey Type I dissection due to aortic wall integrity, allowing unhindered extension within the layers. Methods The perioperative data of 3385 patients from the German Registry for Acute Aortic Dissection Type A (GERAADA) were retrospectively analyzed with regard to postoperative outcomes and dissection extension. Patients with DeBakey Type I aortic dissection (n = 2510) were retrospectively identified and divided into two age-groups for comparison: ≤ 69 years (n = 1741) and ≥ 70years (n = 769). Patients with DeBakey type II dissection or connective tissue disease were excluded from the analysis. Results In younger patients (≤ 69 years), aortic dissection involved the supraaortic vessels significantly more often (52.0% vs. 40.1%; p Conclusions Extensive DeBakey Type I aortic dissection is less frequent in older patients ≥70 years than in younger patients. In contrast, younger patients suffer more often from preoperative organ malperfusion and associated complications. Postoperative mortality remains high irrespective of age-groups. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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