Conjunctival involvement in pemphigus vulgaris: a clinical, histopathological and immunofluorescence study
Autor: | Miriam Sandbank, Michael David, Bilhah Hazaz, Arye Rothem, P. Feuerman, Emmilia Hodak, Israel Kremer |
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Rok vydání: | 1990 |
Předmět: |
Adult
Male medicine.medical_specialty Pathology Conjunctiva Eye disease Fluorescent Antibody Technique Hyperemia Dermatology Immunofluorescence medicine Humans skin and connective tissue diseases Direct fluorescent antibody Aged integumentary system medicine.diagnostic_test business.industry Pemphigus vulgaris Complement C3 Middle Aged medicine.disease Conjunctivitis humanities Pemphigus medicine.anatomical_structure Immunoglobulin G Mucoid discharge Histopathology Female business |
Zdroj: | The British journal of dermatology. 123(5) |
ISSN: | 0007-0963 |
Popis: | SUMMARY Eleven patients with pemphigus vulgaris and with eye complaints had histopathological and direct immunofluorescence (DIF) studies on biopsies of their conjunctivae. In eight of the patients the ocular symptoms preceded the other manifestations of pemphigus. None of the 11 patients had any detectable conjunctival blisters or erosions. The conjunctivitis in three of the patients proved on histopathology and DIF to be a manifestation of pemphigus vulgaris. In the remaining patients, conjunctival hyperaemia with or without a mucoid discharge was observed, but there were no specific histopathological features, although one of them had a positive DIF. |
Databáze: | OpenAIRE |
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