Management Principles Associated With Cytokine Release Syndrome
| Autor: | Channing Vail Dudley, Rhea Micci Simons, Brittney Baer |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Receptors Antigen T-Cell Immunotherapy Adoptive 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Tocilizumab Neoplasms medicine Humans 030212 general & internal medicine Adverse effect Intensive care medicine Receptors Chimeric Antigen Oncology (nursing) business.industry Oncology Nursing Neurotoxicity Immunotherapy medicine.disease Chimeric antigen receptor Cytokine release syndrome chemistry 030220 oncology & carcinogenesis Management principles Car t cells Cytokine Release Syndrome business |
| Zdroj: | Seminars in Oncology Nursing. 35:150931 |
| ISSN: | 0749-2081 |
| DOI: | 10.1016/j.soncn.2019.08.010 |
| Popis: | Objective To discuss current recommendations and resources for nurses to ensure they advocate for patients with cytokine release syndrome (CRS). Data Sources A literature search using key terms: cytokine release syndrome, neurotoxicity, CAR T, adverse events. Conclusion Chimeric antigen receptor (CAR) T-cell immunotherapy is a growing and rapidly changing field of research. Prompt recognition and management of the side effects of CAR T-cell therapy is pivotal to the safe outcomes of patients. As patients are treated with these novel therapies, additional recommendations and standards for treating CRS and neurotoxicity will occur. Implication for Nursing Practice Nursing plays a pivotal role in the CAR T patients’ treatment course because they are the first line of defense in the care of these patients. Providers and patients both rely on nursing knowledge and training to recognize symptoms of CRS and neurotoxicity. With the early recognition of the signs and symptoms of CRS and neurotoxicity, nursing will help improve the outcomes of the patients receiving CAR T-cell therapy. |
| Databáze: | OpenAIRE |
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