Anaplastic large cell (Ki-1) lymphoma with histiocytic phenotype simulating carcinoma
| Autor: | Peter M. Banks, John D. Metter, D. Craig Allred |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Pathology
medicine.medical_specialty Malignant histiocytosis Biology Diagnosis Differential Immunoenzyme Techniques Reticulosarcoma Carcinoma medicine Humans Histiocyte Antibodies Monoclonal Histiocytes General Medicine DNA Neoplasm Middle Aged medicine.disease Lymphoma Histiocytosis Microscopy Electron Phenotype Female Sarcoma Lymph Nodes Lymphoma Large B-Cell Diffuse DNA Probes Diffuse large B-cell lymphoma |
| Zdroj: | American journal of clinical pathology. 94(4) |
| ISSN: | 0002-9173 |
| Popis: | Histiocytic and epithelial cell types share many cytomorphologic and functional characteristics; it is predictable, therefore, that corresponding malignancies might be difficult to distinguish. Described is the case of a 52-year-old woman in whom disseminated anaplastic large-cell lymphoma simulated carcinomatosis by conventional morphologic criteria. Evidence of histiocytic differentiation was derived from immunocytochemical, fine structural, and genetic probe analyses. The diagnosis of histiocytic neoplasia is discussed in relation to categories previously termed malignant histiocytosis, "Ki-1" lymphoma, and regressing atypical histiocytosis, and comparisons are made with animal tumor models. |
| Databáze: | OpenAIRE |
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