Laboratory Investigation of Myeloproliferative Neoplasms (MPNs): Recommendations of the Canadian Mpn Group

Autor: Harold J. Olney, Jaroslav F. Prchal, Anna Porwit, Brian Leber, Suzanne Kamel-Reid, Vincent Éthier, Linda Foltz, Lambert Busque, Vikas Gupta, Shireen Sirhan, Radmila Day, Aly Karsan
Rok vydání: 2016
Předmět:
Zdroj: American journal of clinical pathology. 146(4)
ISSN: 1943-7722
Popis: Objectives: To standardize diagnostic investigations for myeloproliferative neoplasms (MPNs) to increase homogeneity in patient care and to streamline diagnostic approaches in the most efficient and cost-effective manner. Methods: The development of Canadian expert consensus recommendations for the diagnosis of MPNs began with a review of the following: clinical evidence, daily practice, existing treatment guidelines, and availability of diagnostic tools. Each group member was assigned a specific topic, which they discussed with the entire group during several consensus meetings. Results: This document provides the Canadian MPN group’s recommendations, proposed diagnostic algorithms, and background evidence upon which decisions were made. Conclusions: Standardization of diagnostic investigations will increase homogeneity in patient care and provide a foundation for future clinical research in this rapidly evolving therapeutic area. Streamlining diagnostic approaches in the most efficient and cost-effective manner will also result in significant cost saving for the health care system.
Databáze: OpenAIRE