Insulin Resistance and Serum Magnesium Concentrations among Women with Polycystic Ovary Syndrome
| Autor: | Kristen P Hamilton, Amina Haggag, Anna Parker, Rena Zelig |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty endocrine system diseases Medicine (miscellaneous) Physiology 030209 endocrinology & metabolism Review English language Carbohydrate metabolism serum magnesium Hypomagnesemia 03 medical and health sciences Dietary interventions 0302 clinical medicine Insulin resistance insulin resistance Epidemiology medicine polycystic ovary syndrome (PCOS) 030109 nutrition & dietetics Nutrition and Dietetics business.industry Polycystic ovary syndrome (PCOS) medicine.disease Polycystic ovary supplementation glycemic control diet business Food Science |
| Zdroj: | Current Developments in Nutrition |
| ISSN: | 2475-2991 |
| DOI: | 10.1093/cdn/nzz108 |
| Popis: | Polycystic ovary syndrome (PCOS) affects ∼1 in 10 women worldwide. Hypomagnesemia may worsen insulin resistance (IR) due to the role magnesium (Mg) plays in glucose metabolism. This review explores the relation between serum Mg and IR among women with PCOS. A review of primary research focusing on both serum Mg and women with PCOS was conducted from 2011 to 2019. Studies reviewed included human subjects, written in the English language, and limited to community-dwelling women aged ≥18 y. A total of 7 articles were reviewed. The findings from 4 epidemiological analytic studies evaluating serum Mg status suggest there may be a relation between serum Mg concentrations and IR among women with PCOS. However, among the 3 experimental trials, Mg supplementation inconsistently impacted IR among women with PCOS. Women with PCOS are more likely to underconsume Mg-rich foods and have a greater likelihood of lower serum Mg concentrations. Although it remains unclear if dietary Mg and/or supplementation should be a nutritional strategy for all women with PCOS, current research indicates an association between adequate Mg status and improved IR. Further research evaluating dietary interventions and supplementation is warranted. |
| Databáze: | OpenAIRE |
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