Synthesis of Trisubstituted Vinyl Sulfides via Oxidative Thiolation Initiated Cascade Reaction of Alkynoates with Thiols
| Autor: | Lijun Zhang, Jianlin Han, Yi Pan, Shengyang Ni, Haibo Mei, Wenzhong Zhang |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Chemistry Decarboxylation Aryl Organic Chemistry Oxidative phosphorylation 010402 general chemistry 01 natural sciences Combinatorial chemistry 0104 chemical sciences chemistry.chemical_compound Cascade reaction Thiol Organic chemistry Bond cleavage |
| Zdroj: | The Journal of Organic Chemistry. 81:9470-9475 |
| ISSN: | 1520-6904 0022-3263 |
| DOI: | 10.1021/acs.joc.6b01770 |
| Popis: | A thiolation initiated cascade reaction of aryl alkynoates has been developed with thiol as a coupling partner. This radical process has been demonstrated to proceed through S-H bond cleavage, thiolation of alkynoate, aryl migration, and decarboxylation. This reaction tolerates a wide scope of substrates resulting in good chemical yields, which provides an easy and practical strategy for preparation of trisubstituted vinyl sulfides. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|