Possible Synergy Between Electroconvulsive Therapy and Imipramine: A Case Report
| Autor: | Tom K. Birkenhäger, Esther M. Pluijms |
|---|---|
| Přispěvatelé: | Psychiatry |
| Rok vydání: | 2016 |
| Předmět: |
Imipramine
medicine.medical_specialty medicine.drug_class medicine.medical_treatment Tricyclic antidepressant Psychotic depression Antidepressive Agents Tricyclic behavioral disciplines and activities 03 medical and health sciences 0302 clinical medicine Electroconvulsive therapy Internal medicine mental disorders Full remission Humans Medicine In patient Electroconvulsive Therapy Depressive Disorder Major Antidepressant efficacy business.industry Middle Aged medicine.disease Combined Modality Therapy 030227 psychiatry Psychiatry and Mental health Major depressive disorder Female business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Journal of Psychiatric Practice, 22(6), 478-480. Lippincott Williams & Wilkins |
| ISSN: | 1538-1145 1527-4160 |
| DOI: | 10.1097/pra.0000000000000192 |
| Popis: | This report describes a 63-year-old woman, who had experienced 3 previous episodes of severe major depressive disorder. The first 2 episodes responded to treatment with antidepressants, whereas the third episode was accompanied by psychotic features and responded well to treatment with electroconvulsive therapy (ECT). After a severe relapse, the patient responded very slowly to a second course of ECT and failed to achieve full remission. Within a few weeks, she had another severe relapse and responded very rapidly to a combination of ECT and imipramine. The possible enhancement of the antidepressant efficacy of ECT by combining it with a tricyclic antidepressant (TCA) has received little study, although the literature provides some evidence for a synergy between ECT and TCAs. Combining ECT with a TCA may be a useful strategy in patients who fail to achieve full remission or who experience a rapid relapse. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|