Consumption of extra-virgin olive oil rich in phenolic compounds has beneficial antioxidant effects in healthy human adults
| Autor: | Franz Martín, Genoveva Berná, María-Jesús Oliveras-López, Enrique Jurado-Ruiz, Herminia López García de la Serrana |
|---|---|
| Přispěvatelé: | Junta de Andalucía |
| Rok vydání: | 2014 |
| Předmět: |
Antioxidant
medicine.medical_treatment Extra-virgin olive oil Medicine (miscellaneous) Peripheral blood mononuclear cell Superoxide dismutase medicine TX341-641 Food science chemistry.chemical_classification Nutrition and Dietetics biology Nutrition. Foods and food supply Glutathione peroxidase Polyphenols Nutritional intervention study Enzyme assay Enzyme chemistry Biochemistry UPLC–MS Catalase Polyphenol biology.protein Antioxidant enzymes Gene expression Food Science |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname Journal of Functional Foods, Vol 10, Iss, Pp 475-484 (2014) |
| ISSN: | 1756-4646 |
| Popis: | Extra-virgin olive oil (EVOO) possesses beneficial health effects due to its antioxidant activity. In a controlled before-and-after supplementation trial (45 healthy adults), we examined the effects of daily consumption (30 days (d), 50 mL/d) of EVOO rich in phenolic compounds, antioxidant activity and antioxidant enzymes (catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPX)). Participants completed for 30 d a 24-h dietary record. Anthropometric characteristics, body composition, glycemia, plasma lipid profile, plasma polyphenols, total antioxidant capacity, erythrocyte antioxidant enzyme activity, peripheral blood mononuclear cells (PBMC) gene expression were recorded. EVOO supplementation did not modify the first four parameters. Significant increases in plasma antioxidant capacity and antioxidant enzyme activity (CAT, GPX) were observed. Significant increase in SOD and decrease in CAT gene expression were detected. Daily consumption of EVOO rich in phenolic compounds by healthy adults improved their antioxidant status and modified their antioxidant gene expression levels without affecting metabolic parameters. The present study was supported by Grupos PAI (Grupo BIO311), Junta de Andalucía. |
| Databáze: | OpenAIRE |
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