Optical sensing in microfluidic lab-on-a-chip by femtosecond-laser-written waveguides

Autor: Roberto Osellame, Rebeca Martínez Vázquez, Marcella Chiari, Giulio Cerullo, Hugo Hoekstra, C. Dongre, Roberta Ramponi, Hans H. van den Vlekkert, Markus Pollnau, Marina Cretich
Rok vydání: 2008
Předmět:
Zdroj: Analytical & bioanalytical chemistry
393 (2009): 1209–1216.
info:cnr-pdr/source/autori:Martinez V.R.; Osellame R.; Cretich M.; Chiari M.; Dongre C.; Hoekstra H.J.; Pollnau M.; van den Vlekkert H.; Ramponi R.; Cerullo G./titolo:Optical sensing in microfluidic lab-on-a-chip by femtosecond-laser-written waveguides/doi:/rivista:Analytical & bioanalytical chemistry (Print)/anno:2009/pagina_da:1209/pagina_a:1216/intervallo_pagine:1209–1216/volume:393
Analytical and bioanalytical chemistry, 393(4), 1209-1216. Springer
ISSN: 1618-2650
1618-2642
DOI: 10.1007/s00216-008-2399-8
Popis: We use direct femtosecond laser writing to integrate optical waveguides into a commercial fused silica capillary electrophoresis chip. High-quality waveguides crossing the microfluidic channels are fabricated and used to optically address, with high spatial selectivity, their content. Fluorescence from the optically excited volume is efficiently collected at a 90 degree angle by a high numerical aperture fiber, resulting in a highly compact and portable device. To test the platform we performed electrophoresis and detection of a 23-mer oligonucleotide plug. Our approach is quite powerful because it allows the integration of photonic functionalities, by simple post-processing, into commercial LOCs fabricated with standard techniques.
Databáze: OpenAIRE
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