Biological profile and response to anti-pneumocystis agents of Pneumocystis carinii in cell culture
| Autor: | D. D. Pifer, Linda Pifer, Diane R. Woods |
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| Rok vydání: | 1983 |
| Předmět: |
Male
Time Factors Sulfamethoxazole Pentamidine Isethionate Amidines Biology Trimethoprim Microbiology Biological profile Trimethoprim Sulfamethoxazole Drug Combination parasitic diseases medicine Animals Pharmacology (medical) Cells Cultured Pentamidine Organism Pharmacology Pneumocystis Rats Inbred Strains Virology In vitro Rats Drug Combinations Infectious Diseases Pneumocystis carinii Cell culture Research Article medicine.drug |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 24:674-678 |
| ISSN: | 1098-6596 0066-4804 |
| Popis: | Although the growth characteristics of Pneumocystis carinii have been described in several cell culture systems, the response of this organism to the drugs of choice, trimethoprim-sulfamethoxazole and pentamidine isethionate, have not been described in vitro. The effect of various concentrations of drugs against P. carinii on the growth of this potentially hazardous opportunistic organism as well as the methodology for in vitro assay of these agents have been detailed. Fluorescence profiles illustrating size ranges of trophozoites and cysts derived from cell culture are described. |
| Databáze: | OpenAIRE |
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