Inflammation dynamics after praziquantel treatment of Schistosoma haematobium reflected by urinary eosinophil cationic protein

Autor:	Moussa Sacko, Shona Wilson, Hassan K M Fofana, Birgitte J. Vennervald, Henry Madsen, Chalotte Willemann Stecher, Aly Landouré, Mamadou Traoré, Claus M. Reimert, Adama D. Keita
Rok vydání:	2017
Předmět:	Male 0301 basic medicine Urine Kidney Gastroenterology Praziquantel Cohort Studies Schistosomiasis haematobia fluids and secretions 0302 clinical medicine INFECTION Schistosomiasis Child Anthelmintics Schistosoma haematobium Eosinophil cationic protein biology SCHOOLCHILDREN WOMEN General Medicine Dynamics Infectious Diseases medicine.anatomical_structure Child Preschool Female medicine.drug Adult medicine.medical_specialty Adolescent Urinary system Urinary Bladder education 030231 tropical medicine MORBIDITY Young Adult 03 medical and health sciences Internal medicine parasitic diseases medicine Animals Humans Parasite Egg Count Hematuria Inflammation business.industry Eosinophil Cationic Protein Public Health Environmental and Occupational Health FEMALE GENITAL SCHISTOSOMIASIS medicine.disease biology.organism_classification ECP Confidence interval 030104 developmental biology MARKER EGG EXCRETION HEMATURIA Parasitology KENYA business Biomarkers
Zdroj:	Stecher, C W, Fofana, H K M, Madsen, H, Wilson, S, Keita, A D, Landoure, A, Traore, M S, Vennervald, B J, Reimert, C M & Sacko, M 2017, ' Inflammation dynamics after praziquantel treatment of Schistosoma haematobium reflected by urinary eosinophil cationic protein ', Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 111, no. 7, pp. 316-324 . https://doi.org/10.1093/trstmh/trx057
ISSN:	1878-3503 0035-9203
Popis:	Background This cohort study assessed urinary eosinophil cationic protein (ECP) as an indicator for urinary tract morbidity and inflammation indication related to single-dose or dual-dose praziquantel (PZQ) treatment. Methods Urinary ECP was measured at baseline, 24 h and 9 weeks after treatment (baseline 305, follow-up 204 participants, ages 2-40 years). Results ECP was significantly associated with the intensity of infection at baseline (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3197d80775c727a735d9bc0a52a94a3 https://doi.org/10.1093/trstmh/trx057 Zobrazit plný text záznamu