Prevalence of SARS-CoV-2 among high-risk populations in Lomé (Togo) in 2020
| Autor: | Anoumou Dagnra, K.S. Adjoh, Mohaman Awalou Djibril, Koffi Segbeaya Komlanvi, Yem-bla Kao, Mireille Prine-David, Mounerou Salou, Didier K. Ekouevi, Simon-Pierre Hamadi Assane, Amétépé Agbobli, Sossinou Marcel Awoussi, Moustafa Mijiyawa, Edem Goeh-Akue, Majesté Ihou Wateba, Josée Nayo-Apetsianyi, Fifonsi Adjidossi Gbeasor-Komlanvi, Yao Rodion Konu, Rebecca Kinde-Sossou, Martin Kouame Tchankoni, Innocent Kpeto, Ameyo M. Dorkenoo, Agbeko Tamekloe, Wemboo Afiwa Halatoko, Paul Pana, Arnold Junior Sadio, Issaka Maman |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
RNA viruses 0301 basic medicine Viral Diseases Oropharyngeal swab Coronaviruses Epidemiology Physiology Cross-sectional study Social Sciences Antibodies Viral Biochemistry Serology Geographical Locations Medical Conditions Law Enforcement 0302 clinical medicine Risk Factors Immune Physiology Pandemic Prevalence Medicine Targeted screening 030212 general & internal medicine Pathology and laboratory medicine Virus Testing Immunoassay Immune System Proteins Multidisciplinary Middle Aged Medical microbiology Police Professions Infectious Diseases Togo Viruses RNA Viral Female SARS CoV 2 Pathogens Coronavirus Infections Research Article Adult SARS coronavirus Coronavirus disease 2019 (COVID-19) Science Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Pneumonia Viral Immunology Real-Time Polymerase Chain Reaction Microbiology Antibodies Road transport Betacoronavirus 03 medical and health sciences Diagnostic Medicine Humans Pandemics Medicine and health sciences Air transport High risk populations Biology and life sciences SARS-CoV-2 business.industry Organisms Viral pathogens COVID-19 Proteins Outbreak Covid 19 Microbial pathogens Cross-Sectional Studies 030104 developmental biology Medical Risk Factors People and Places Africa Law and Legal Sciences Population Groupings business Criminal Justice System Demography |
| Zdroj: | PLoS ONE, Vol 15, Iss 11, p e0242124 (2020) PLoS ONE |
| Popis: | Background In December 2019, the COVID-19 outbreak began in China and quickly spread throughout the world and was reclassified as a pandemic in March 2020. The first case of COVID-19 was declared in Togo on March 5. Two months later, few data were available to describe the circulation of the new coronavirus in the country. Objective This survey aimed to estimate the prevalence of SARS-CoV-2 in high-risk populations in Lomé. Materials and methods From April 23, 2020, to May 8, 2020, we recruited a sample of participants from five sectors: health care, air transport, police, road transport and informal. We collected oropharyngeal swabs for direct detection through real-time reverse transcription polymerase chain reaction (rRT-PCR) and blood for antibody detection by serological tests. The overall prevalence (current and past) of infection was defined by positivity for both tests. Results A total of 955 participants with a median age of 36 (IQR 32–43) were included, and 71.6% (n = 684) were men. Approximately 22.1% (n = 212) were from the air transport sector, 20.5% (n = 196) were from the police sector, and 38.7% (n = 370) were from the health sector. Seven participants (0.7%, 95% CI: 0.3–1.6%) had a positive rRT-PCR test result at the time of recruitment, and nine (0.9%, 95% CI: 0.4–1.8%) were seropositive for IgM or IgG against SARS-CoV-2. We found an overall prevalence of 1.6% (n = 15), 95% CI: 0.9–2.6%. Conclusion The prevalence of SARS-CoV-2 infection among high-risk populations in Lomé was relatively low and could be explained by the various measures taken by the Togolese government. Therefore, we recommend targeted screening. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|