Determinants of Expiratory Flow Limitation in Healthy Women during Exercise
| Autor: | Jordan A. Guenette, A. William Sheel, Sabrina S. Wilkie, Paolo B. Dominelli, Glen E. Foster |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
medicine.medical_specialty business.industry Flow limitation VO2 max Exhalation Physical Therapy Sports Therapy and Rehabilitation Young Adult FEV1/FVC ratio Oxygen Consumption Internal medicine Cardiology Physical therapy Humans Medicine Aerobic exercise Female Orthopedics and Sports Medicine Lung volumes Exercise physiology Pulmonary Ventilation business Exercise Peak exercise |
| Zdroj: | Medicine & Science in Sports & Exercise. 43:1666-1674 |
| ISSN: | 0195-9131 |
| DOI: | 10.1249/mss.0b013e318214679d |
| Popis: | Expiratory flow limitation (EFL) can occur in healthy young women during exercise. We questioned whether the occurrence and severity of EFL were related to aerobic fitness or anatomical factors.Twenty-two healthy young (40 yr) women performed a progressive cycle test to exhaustion. The subjects' maximum expiratory flow-volume curve was compiled from several effort-graded vital capacity maneuvers before and after exercise. The maximum expiratory flow-volume curve, along with inspiratory capacity maneuvers, was used to determine lung volumes and expiratory flows and to quantify EFL. To determine relative airway size, we used a ratio sensitive to both airway size and lung volume, called the dysanapsis ratio. The subjects were partitioned into two groups based upon the appearance of5% EFL.Ten subjects showed EFL during exercise. Forced vital capacities (4.4 ± 0.4 vs 3.7 ± 0.4 L, P0.001) and forced expiratory flows for any given lung volume were significantly larger in the non-expiratory flow-limited (NEFL) group. The NEFL group's dysanapsis ratio was significantly larger than that of the EFL group (0.27 ± 0.06 vs 0.21 ± 0.04, respectively, P0.05), indicating larger airways in the NEFL group. There was no difference between the NEFL and EFL groups with respect to maximal aerobic capacity (50.8 ± 10.0 vs 46.7 ± 5.9 mL·kg(-1)·min(-1), respectively, P = 0.264). At peak exercise, the NEFL group had a significantly higher end-expiratory lung volume than the EFL group (40.1% ± 4.8% vs 33.7% ± 5.7% FVC, respectively, P0.05).We conclude that EFL in women can largely be explained by anatomical factors that influence the capacity to generate flow and volume during exercise rather than fitness per se. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|