A rare case of centric fission and fusion in a river buffalo (Bubalus bubalis, 2n=50) cow with reduced fertility
Autor: | Domenico Incarnato, Fiorella Sarubbi, A. Caputi-Jambrenghi, V. Genualdo, Leopoldo Iannuzzi, Angela Perucatti, Vincenzo Peretti, G.P. Di Meo, Alessandra Iannuzzi, G. Vonghia |
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Přispěvatelé: | DI MEO, G. P., Perucatti, A., Genualdo, V., Iannuzzi, A., Sarubbi, F., CAPUTI JAMBREGHI, A., Incarnato, D., Peretti, Vincenzo, Vonghia, G., Iannuzzi, L. |
Rok vydání: | 2010 |
Předmět: |
Buffaloes
Offspring Robertsonian translocation Chromosomal translocation medicine.disease_cause Andrology Centric fusion Genetics medicine Animals Molecular Biology Genetics (clinical) In Situ Hybridization Fluorescence biology Chromosome biology.organism_classification medicine.disease River buffalo Chromosome Banding Karyotyping Chromosome abnormality Cattle Female Bubalus Infertility Female |
Zdroj: | Cytogenetic and genome research (Print. ed.) 132 (2010): 26–30. info:cnr-pdr/source/autori:G.P. Di Meo, A. Perucatti, V. Genualdo, A. Iannuzzi, F. Sarubbi, A. Caputi-Jambrenghi, D. Incarnato, V. Peretti, G. Vonghia, L. Iannuzzi/titolo:A rare case of centric fission and fusion in a river buffalo (Bubalus bubalis, 2n=50) cow with reduced fertility/doi:/rivista:Cytogenetic and genome research (Print. ed.)/anno:2010/pagina_da:26/pagina_a:30/intervallo_pagine:26–30/volume:132 Cytogenetic and genome research (Print. ed.) 132 (2011): 26–30. doi:10.1159/000318011. info:cnr-pdr/source/autori:Di Meo GP, Perucatti A, Genualdo V, Iannuzzi A, Sarubbi F, Caputi-Jambrenghi A, Incarnato D, Peretti V, Vonghia G, Iannuzzi L./titolo:A Rare Case of Centric Fission and Fusion in a River Buffalo (Bubalus bubalis, 2n = 50) Cow with Reduced Fertility./doi:10.1159%2F000318011./rivista:Cytogenetic and genome research (Print. ed.)/anno:2011/pagina_da:26/pagina_a:30/intervallo_pagine:26–30/volume:132 |
Popis: | A 5-year-old river buffalo cow underwent cytogenetic investigation since it had only one male offspring, apparently with normal body constitution, which died one month after birth. The female carrier had normal body conformation and internal sex adducts, as revealed by rectal palpation performed by a specialist veterinary practitioner. The cow was found to carry a complex and rare chromosome abnormality. Indeed, a centric fission of one river buffalo (BBU) chromosome 1 with a subsequent (or simultaneous) centric fusion of BBU1p with BBU23 was revealed by both RBA-banding and specific molecular markers of BBU1p (DEFB1) and BBU23 (ACTA2). CBA-banding revealed a pale, very small C-band in the der1 (BBU1q) and a prominent C-band on the new biarmed chromosome originated by rob(1p;23). Both telomeric probes and AgNOR staining confirmed the Robertsonian translocation (rob), both FITC-signals and the NORs (BBU23) being telomerically located. Furthermore, telomeric signals on der1 (BBU1q) indicate that these 2 chromosomal events may be the result of a reciprocal translocation which occurred between BBU1 and BBU23. |
Databáze: | OpenAIRE |
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