Antidepressant drug interactions in the elderly
| Autor: | Roger J. Cadieux |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Drug
Aging medicine.medical_specialty media_common.quotation_subject Antidepressive Agents Tricyclic Affect (psychology) Pharmacological treatment Cytochrome P-450 Enzyme System Dopamine Uptake Inhibitors Risk Factors medicine Humans Disease Drug Interactions Psychiatry Intensive care medicine Depression (differential diagnoses) Aged media_common Adrenergic Uptake Inhibitors business.industry Contraindications Critical factors General Medicine Antidepressive Agents Diet Increased risk Polypharmacy Antidepressive Agents Second-Generation Body Burden Antidepressant Drug Monitoring business Selective Serotonin Reuptake Inhibitors Drug metabolism |
| Zdroj: | Postgraduate Medicine. 106:231-249 |
| ISSN: | 1941-9260 0032-5481 |
| DOI: | 10.3810/pgm.1999.11.780 |
| Popis: | Antidepressant treatment in patients 65 years of age or older carries increased risks of adverse drug events because of age-related physiologic changes, polypharmacy, and individual variability in drug metabolism (due to genetic factors, concurrent disease, diet, and consumption habits). Reduction of total drug burden, adjustment of dose levels, and careful selection of an appropriate agent are important steps toward avoiding adverse drug interactions, In addition, the documented and potential drug interactions of the various classes of antidepressants, and specific agents within each class, should be considered. Each elderly patient should be treated individually and monitored carefully during the initiation and maintenance of antidepressant therapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|