DNA synthesis studies in pre-meiotic mouse oogenesis

Autor:	G. Jagiello, Weng Kong Sung, J. Van't Hof
Rok vydání:	1986
Předmět:	DNA Replication Cell division Somatic cell Biology Tritium Oogenesis chemistry.chemical_compound Mice Meiosis Animals Replicon DNA synthesis Cell Cycle DNA replication Cell Biology Cell biology Kinetics chemistry Biochemistry Oocytes Autoradiography Female DNA Thymidine
Zdroj:	Experimental cell research. 163(2)
ISSN:	0014-4827
Popis:	DNA fiber autoradiography was used in mouse oogenesis to test Callan's hypothesis that a longer S phase results from a reduction in the number of active initiation sites. The data indicated that the premeiotic increase in the duration of S phase in mouse oogenesis was characterized by a rapid initial rate of chain growth and a larger replicon size when compared with replicating DNA of somatic mouse cells. These findings were at variance with those in mouse spermatogenesis and also did not support the Callan hypothesis of activation site repression.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2fd923db80f6f6031b528bb68dd9fd5 https://pubmed.ncbi.nlm.nih.gov/3956583 Zobrazit plný text záznamu