Allergy-induced preterm labor after the ingestion of shellfish
Autor: | Roberto Romero, Lami Yeo, Ronald F. Lamont, Hernan Muñoz, Juan Pedro Kusanovic, Ricardo Gomez |
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Rok vydání: | 2009 |
Předmět: |
Adult
Chlorpheniramine Allergy Amniotic fluid Inflammation Betamethasone Article Uterine contraction Atopy Uterine Contraction Obstetric Labor Premature Pregnancy Anti-Allergic Agents Animals Humans Medicine Ingestion Glucocorticoids Shellfish business.industry Pregnancy Outcome Obstetrics and Gynecology medicine.disease Nephropidae Pediatrics Perinatology and Child Health Immunology Female medicine.symptom business Food Hypersensitivity medicine.drug |
Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 23:351-359 |
ISSN: | 1476-4954 1476-7058 |
Popis: | Preterm parturition is a syndrome caused by several mechanisms of disease, including intrauterine infection/inflammation, uteroplacental ischemia, uterine overdistension, cervical disease, maternal/fetal stress, abnormal allogeneic responses, allergic reactions, and unknown insults. An allergic-like mechanism was proposed as a potential etiology for the preterm parturition syndrome, based on the observation that eosinophils were present in the amniotic fluid in a fraction of women with preterm labor and a history of allergy, coupled with the observation that conditioned media from degranulated mast cells (the effector cells of type 1 hypersensitivity) induced contractility of human myometrial strips. This communication describes a case of a pregnant woman who had an allergic reaction and regular uterine contractions after the ingestion of lobster meat, to which she was known to be allergic. Preterm labor subsided after the treatment of antihistamines and steroids. The patient subsequently delivered at term. At follow-up, the child was diagnosed with atopy and asthma, and required frequent use of inhaled corticosteroids and beta-2 adrenergic agents. The immunological basis for preterm labor induced by an allergic-like reaction (hypersensitivity) is reviewed. |
Databáze: | OpenAIRE |
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