Objective Measurement of Adherence to Out-Patient Airway Clearance Therapy by High-Frequency Chest Wall Compression in Cystic Fibrosis
| Autor: | Jeremiah S Menk, Theresa A. Laguna, Warren E. Regelmann, Philippe Gaillard, Christina L. Mikesell, Andrew Wey, Robert R. Kempainen |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Airway clearance Respiratory Therapy Adolescent Cystic Fibrosis Monitoring Ambulatory Critical Care and Intensive Care Medicine Cystic fibrosis Pulmonary function testing 03 medical and health sciences Young Adult 0302 clinical medicine High-Frequency Chest Wall Compression Drainage Postural 030225 pediatrics Internal medicine Chart review Forced Expiratory Volume Outpatients medicine Humans Child Lung Original Research business.industry Objective measurement General Medicine medicine.disease Chest Wall Oscillation Treatment Outcome 030228 respiratory system Physical therapy Disease Progression VEST Patient Compliance Female Analysis of variance business |
| Zdroj: | Respiratory care. 62(7) |
| ISSN: | 1943-3654 |
| Popis: | BACKGROUND: Objective measures of adherence to high-frequency chest wall compression (HFCWC), a form of airway clearance therapy for patients with cystic fibrosis, are lacking. We used a novel electronic monitoring device integrated into an HFCWC vest to measure adherence compared with self-reported adherence. We determined factors that influenced adherence and how adherence correlated with baseline pulmonary function and pulmonary exacerbations. METHODS: Data were collected by direct measurement of date, time of day, and duration of HFCWC use to determine the number of daily treatments and daily duration of treatments. Chart review provided prescribed airway clearance therapy treatment and demographic and clinical information. Subject and caregiver report of the daily number of airway clearance therapy treatments was obtained by telephone interviews. Analysis used 2-sample and paired t test, analysis of variance, and linear regression. RESULTS: Average adherence was 69%. Adherence was highest in children (82%, P = .02) and those receiving assistance with treatment (82%, P < .001). Subjects overestimated therapy duration from a mean ± SD of 127 ± 169% by adults to 19.2 ± 26.3% by parents or guardians of children. Average adherence decreased with increasing prescribed therapy time (P = .02). Average daily therapy time and adherence had significant positive associations with baseline FEV(1) percent of predicted (P = .02 and P = .02, respectively) and negative associations with pulmonary exacerbations during the pre-study period and at baseline (P = .044 and P = .02, respectively). CONCLUSIONS: Greater adherence to HFCWC measured directly by a novel recorder was associated with better baseline pulmonary function and fewer exacerbations in the pre-study and baseline period. Adherence decreased with age and prescribed therapy time and increased with therapy assistance. Self-report overestimation is large and thus not an accurate measure of adherence. |
| Databáze: | OpenAIRE |
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