Small but mighty: old and new parvoviruses of veterinary significance
| Autor: | Gerlinde R. Van de Walle, Joy E. Tomlinson, Robert Lopez-Astacio, Colin R. Parrish, Mason Jager |
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| Rok vydání: | 2021 |
| Předmět: |
Veterinary medicine
Viral metagenomics food.ingredient viruses Vertebrate Animals Review Amdoparvovirus Infectious and parasitic diseases RC109-216 Disease Parvoviridae Parvoviridae Infections Parvovirus food Virology Animal parvoviruses Animals Pathogenicity Phylogeny biology Family Parvoviridae Chaphamaparvovirus biology.organism_classification Copiparvovirus Infectious Diseases Healthy individuals Identification (biology) Metagenomics Viral therapeutics |
| Zdroj: | Virology Journal, Vol 18, Iss 1, Pp 1-29 (2021) Virology Journal |
| ISSN: | 1743-422X |
| DOI: | 10.1186/s12985-021-01677-y |
| Popis: | In line with the Latin expression “sed parva forti” meaning “small but mighty,” the family Parvoviridae contains many of the smallest known viruses, some of which result in fatal or debilitating infections. In recent years, advances in metagenomic viral discovery techniques have dramatically increased the identification of novel parvoviruses in both diseased and healthy individuals. While some of these discoveries have solved etiologic mysteries of well-described diseases in animals, many of the newly discovered parvoviruses appear to cause mild or no disease, or disease associations remain to be established. With the increased use of animal parvoviruses as vectors for gene therapy and oncolytic treatments in humans, it becomes all the more important to understand the diversity, pathogenic potential, and evolution of this diverse family of viruses. In this review, we discuss parvoviruses infecting vertebrate animals, with a special focus on pathogens of veterinary significance and viruses discovered within the last four years. |
| Databáze: | OpenAIRE |
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