Eosinophilic airway inflammation in a cynomolgus monkey
| Autor: | N. Shirai, F. J. Geoly |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Pathology
medicine.medical_specialty Allergy Respiratory Tract Diseases Inflammation Lesion Eosinophilic Eosinophilia Medicine Animals Asthma Lung General Veterinary business.industry Histocytochemistry Monkey Diseases Histology respiratory system medicine.disease respiratory tract diseases Macaca fascicularis medicine.anatomical_structure Immunology Female medicine.symptom business Airway |
| Zdroj: | Veterinary pathology. 47(2) |
| ISSN: | 1544-2217 |
| Popis: | The present article describes an occurrence of eosinophilic airway inflammation of a 4-year-old female cynomolgus monkey in a vehicle control group of a routine toxicology study. Histologically, the airway lesion was characterized by prominent eosinophilic infiltrates, accompanied by mast cells, lymphocytes, and plasmacytes. The eosinophilic infiltrates were distributed throughout the airway: from trachea through respiratory bronchioles in the lung. The morphological feature of the lesion was indicative of an allergic airway disorder that can occur in humans with asthma. The present case is remarkable in that there is a paucity of reports on naturally occurring allergic airway disorders in nonhuman primates. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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