Non-compressible ABIs are associated with an increased risk of major amputation and major adverse cardiovascular events in patients with critical limb ischemia
| Autor: | Stephen W. Waldo, Ezra A. Amsterdam, Gagan D. Singh, Ehrin J. Armstrong, Misty D. Humphries, Bejan Alvandi, Ellen Brinza, Justin Hildebrand, John R. Laird |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Critical Illness medicine.medical_treatment Comorbidity Kaplan-Meier Estimate 030204 cardiovascular system & hematology Risk Assessment Amputation Surgical California Coronary artery disease Peripheral Arterial Disease 03 medical and health sciences 0302 clinical medicine Ischemia Predictive Value of Tests Risk Factors Diabetes mellitus Internal medicine Humans Medicine Ankle Brachial Index Registries 030212 general & internal medicine Peripheral artery disease (PAD) Adverse effect Aged Proportional Hazards Models Retrospective Studies business.industry Endovascular Procedures Angiography Critical limb ischemia Middle Aged Limb Salvage medicine.disease Surgery Treatment Outcome Amputation Cohort Cardiology Female medicine.symptom Cardiology and Cardiovascular Medicine business Mace |
| Zdroj: | Vascular Medicine. 22:210-217 |
| ISSN: | 1477-0377 1358-863X |
| DOI: | 10.1177/1358863x16689831 |
| Popis: | Ankle–brachial indices (ABIs) are important for the assessment of disease burden among patients with peripheral artery disease. Although low values have been associated with adverse clinical outcomes, the association between non-compressible ABI (ncABI) and clinical outcome has not been evaluated among patients with critical limb ischemia (CLI). The present study sought to compare the clinical characteristics, angiographic findings and clinical outcomes of those with compressible (cABI) and ncABI among patients with CLI. Consecutive patients undergoing endovascular evaluation for CLI between 2006 and 2013 were included in a single center cohort. Major adverse cardiovascular events (MACE) were then compared between the two groups. Among 284 patients with CLI, 68 (24%) had ncABIs. These patients were more likely to have coronary artery disease ( p=0.003), diabetes ( p |
| Databáze: | OpenAIRE |
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