The epidemic cycle of Chlamydia pneumoniae infection in eastern Finland, 1972–1987
| Autor: | J. Tuomilehto, J. Pitkaniemi, M. Karvonen, Pekka Saikku |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Adult
Male Rural Population Urban Population Epidemiology Population Fluorescent Antibody Technique medicine.disease_cause Immunoglobulin G 03 medical and health sciences Sex Factors 0302 clinical medicine Prevalence medicine Humans Chlamydiaceae 030212 general & internal medicine Antibody prevalence education Finland 0303 health sciences education.field_of_study Chlamydia biology 030306 microbiology Age Factors Chlamydia Infections Chlamydophila pneumoniae Middle Aged medicine.disease biology.organism_classification Antibodies Bacterial 3. Good health Infectious Diseases Chlamydiales Immunology biology.protein Female Antibody Research Article Demography |
| Zdroj: | Epidemiology and Infection. 110:349-360 |
| ISSN: | 1469-4409 0950-2688 |
| DOI: | 10.1017/s0950268800068291 |
| Popis: | SUMMARYThe epidemic cycle of Chlamydia pneumoniae infection was examined in two areas in eastern Finland over a period of 15 years, 1972–87. The C. pneumoniae IgG antibody prevalence was determined with 5-year intervals in a random sample of the population aged 25–59 years. The total number of sera studied using immunofluorescence was 2387. In 1972 the antibody prevalence was 57% and it increased to 66% in 1977. Over the next 5 years the prevalence decreased to 44% in 1982, but by 1987 it had again increased to 59%. The temporal variation in prevalence was statistically significant (P < 0·001) and similar for both genders. Throughout the observation period the overall prevalence Mas 7–11% higher in men than in women (P < 0·01). The antibody prevalence increased with age, being the highest among the oldest study subjects of both genders. The periods of high and low prevalence alternated in an epidemic cycle (P < 0·001) of about 10 years |
| Databáze: | OpenAIRE |
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