Determination of lignans and isoflavonoids in human female plasma following dietary supplementation
| Autor: | K. Griffiths, Mark L Wahlqvist, M.S. Morton, Gisela Wilcox |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
medicine.medical_specialty
Linseed Oil Monoamine Oxidase Inhibitors Endocrinology Diabetes and Metabolism Flavonoid Genistein Gas Chromatography-Mass Spectrometry Lignans chemistry.chemical_compound Endocrinology Enterolactone 4-Butyrolactone Internal medicine Neoplasms Blood plasma medicine Humans Enterodiol Chromans chemistry.chemical_classification Lignan Daidzein Australia Estrogens Equol Middle Aged Isoflavones Diet Postmenopause chemistry Food Fortified Female Soybeans Plants Edible |
| Zdroj: | The Journal of endocrinology. 142(2) |
| ISSN: | 0022-0795 |
| Popis: | Plasma levels of the lignans enterodiol and enterolactone, and also the isoflavonic phyto-oestrogens daidzein, equol and genistein, are reported for postmenopausal Australian women consuming a traditional diet supplemented with linseed, soya flour or clover sprouts. Analysis was performed by gas chromatography-mass spectrometry, after enzymatic hydrolysis and ion-exchange chromatography. Following linseed supplementation, combined levels of enterolactone and enterodiol reached 500 ng/ml, whereas after soya flour or clover sprouts the respective concentrations of equol, daidzein and genistein reached 43, 312 and 148 ng/ml. Not all subjects were able to produce equol from daidzein. The possible relationship and role of these weak dietary oestrogens as restraining factors in the development of hormone-dependent cancers in Asian populations is discussed. Journal of Endocrinology (1994) 142, 251–259 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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