Solvent-free synthesis of dibenzo[b,j][1,10]phenanthroline derivatives using Eaton’s reagent as catalyst

Autor:	Karnam Jayarampillai Rajendra Prasad, Rajendran Satheeshkumar
Rok vydání:	2017
Předmět:	010405 organic chemistry Chemistry Phenanthroline Aryl Organic Chemistry Synthon 010402 general chemistry 01 natural sciences Medicinal chemistry Friedländer synthesis 0104 chemical sciences Catalysis Solvent chemistry.chemical_compound Reagent Yield (chemistry) Organic chemistry
Zdroj:	Synthetic Communications. 47:990-998
ISSN:	1532-2432 0039-7911
Popis:	A new class of dibenzo[b,j][1,10]phenanthrolines has been prepared. The synthon acridones were achieved in very good yield by a one-pot reaction of 2-amino-5-chloro or 2′-chloro/flouro-substituted benzophenones with 1,2-cyclohexanedione in the presence of freshly prepared Eaton’s reagent (phosphorus pentoxide–methanesulfonic acid) without solvent, through Friedländer synthesis. Then these intermediates were reacted with 2-amino-3,5-dibromobenzaldehyde to afford 1,3-dibromo-10-chloro-8-aryl-6,7-dihydrodibenzo[b,j][1,10]phenanthroline. Also an one-pot reaction between 2 mol of 2-amino-5-chloro aryl benzophenones with 1 mol of 1,2-cyclohexanedione to get 3,10-dichloro-5,8-diaryl-6,7-dihydrodibenzo[b,j][1,10]phenanthroline has also been reported. The newly synthesized structures of the compounds were deduced by spectroscopic techniques.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e1b39aca3b14acd52bd0e4e92f130e https://doi.org/10.1080/00397911.2017.1301480 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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