Body composition and bone mineral density in postmenopausal women with rheumatoid arthritis
Autor: | O. Dobrovolskaya, A. Yu. Feklistov, N. Demin, N. V. Toroptsova, A. Efremova, O. Nikitinskaya |
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Jazyk: | ruština |
Rok vydání: | 2021 |
Předmět: |
musculoskeletal diseases
rheumatoid arthritis medicine.medical_specialty Immunology Osteoporosis 030209 endocrinology & metabolism Diseases of the musculoskeletal system sarcopenia 03 medical and health sciences 0302 clinical medicine Rheumatology Internal medicine medicine Immunology and Allergy Femoral neck 030203 arthritis & rheumatology Bone mineral body composition Postmenopausal women business.industry medicine.disease musculoskeletal system Trunk Osteopenia Endocrinology medicine.anatomical_structure RC925-935 Rheumatoid arthritis Sarcopenia business bone mineral density |
Zdroj: | Научно-практическая ревматология, Vol 59, Iss 3, Pp 282-287 (2021) |
ISSN: | 1995-4492 1995-4484 |
Popis: | Aim – to study the relationship between body composition and bone mineral density (BMD) in postmenopausal women with rheumatoid arthritis (RA).Material and methods. 68 postmenopausal women, median age 59 [54; 63] years, with RA were included in the study. Bone mineral density (BMD) and body composition were assessed with dual energy X-ray absorptiometry.Results. 33 (48.5%) women had osteopenia, and 17 (25.0%) – osteoporosis (OP). Low lean muscle mass was found in 10 (14.7%) patients. There were positive correlations between different areal BMD and body weight, trunk fat, trunk lean muscle mass and total lean muscle mass. In the multivariate linear regression analysis total lean muscle mass was associated with BMD of lumbar spine (β=0.638; p=0.001) and total hip (β=0.473; p=0.008), and appendicular lean muscle mass, estimated using the appendicular muscle index, with femoral neck BMD (β=0.360; p=0.014).Conclusion. 73.5% of patients with RA had a reduced BMD, and 14.7% women – low muscle mass. The revealed significant association between the lean muscle mass and BMD of lumbar spine and proximal femur indicates the importance of detecting and correcting low lean muscle mass, as well as preventing its decline in order to prevent loss of BMD and osteoporotic fractures. |
Databáze: | OpenAIRE |
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