Spontaneous variation of leukocytospermia in asymptomatic infertile males
| Autor: | Georg Schatzl, Michael Marberger, Thomas Waldhör, Jakob Lackner, Emina Lakovic |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Infertility medicine.medical_specialty Leukocytosis Sterility Semen Semen analysis Asymptomatic Leukocyte Count Leukocytes Humans Medicine Prospective Studies Prospective cohort study Cell Shape Infertility Male Sperm motility Gynecology Sperm Count medicine.diagnostic_test business.industry Obstetrics and Gynecology medicine.disease Spermatozoa Sperm Reproductive Medicine Sperm Motility medicine.symptom business |
| Zdroj: | Fertility and Sterility. 90:1757-1760 |
| ISSN: | 0015-0282 |
| DOI: | 10.1016/j.fertnstert.2007.08.041 |
| Popis: | Objective To investigate the spontaneous variation of leukocytospermia (>1 million/mL) in semen samples from infertile men. Design Prospective cohort study. Setting Andrologic clinic at university hospital. Patient(s) Ninety-nine men evaluating for infertility causes. Intervention(s) Two semen analyses according the World Health Organization criteria combined with urologic investigation without any treatment. Main Outcome measure(s) Spontaneous (downward/upward) variation in leukocyte count, sperm concentration, total motility, and morphology between the two semen samples. Result(s) In the first semen analysis, 21% of men had leukocytospermia. By the second analysis, leukocyte concentrations were within the normal range in 9 of these 21 men, corresponding to a downward variation of 43%. In contrast, 7 of 78 patients with normal leukocyte levels at the first analysis had leukocytospermia at the second analysis, corresponding to an upward variation of 9%. The upward variation rates for sperm concentration, total motility, and morphology were 4%, 17%, and 4%, respectively. Downward variation rates were considerably higher for total motility and morphology (30% and 28%, respectively). Conclusion(s) The rate for spontaneous downward variation of leukocytospermia in the absence of treatment was 43% in this study. This rate should be taken into consideration when treating infertile men with leukocytospermia, because effective medical therapy is still lacking. |
| Databáze: | OpenAIRE |
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