Maydisone, a novel oxime polyketide from the cultures of Bipolaris maydis

Autor:	Thi-Minh-Dinh Tran, Minh-Hiep Dinh, Nguyen-Minh-An Tran, Warinthorn Chavasiri, Thuc-Huy Duong, Jirapast Sichaem, Asshaima Paramita Devi, Ngoc-Hong Nguyen, Van-Kieu Nguyen, Thanh-Nha Tran
Rok vydání:	2020
Předmět:	010405 organic chemistry Stereochemistry Organic Chemistry Plant Science Oxime 01 natural sciences Biochemistry Bipolaris maydis 0104 chemical sciences Analytical Chemistry 010404 medicinal & biomolecular chemistry chemistry.chemical_compound Polyketide chemistry
DOI:	10.6084/m9.figshare.12292901
Popis:	A novel oxime polyketide, maydisone (1), along with two known compounds, 7-hydroxy-2,5-dimethylchromone (2) and 2,5-dimethylbenzoic acid (3) were isolated from the cultures of Bipolaris maydis. Their structures were identified by the application of NMR and MS data analyses and comparison with previous reports. Compound 1 showed the most powerful inhibition of α-glucosidase, with an IC50 value of 68.30 ± 0.83 µM.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c5b191c2b3a705fd10443336fdcecd Zobrazit plný text záznamu