Self-Collected Anterior Nasal and Saliva Specimens versus Healthcare Worker-Collected Nasopharyngeal Swabs for the Molecular Detection of SARS-CoV-2
| Autor: | Hillyard, J. W. Barrett, Kimberly E. Hanson, Richard R. Orlandi, Adam P. Barker, Salika M. Shakir, N. Gilmore |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Saliva Coronavirus disease 2019 (COVID-19) business.industry Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) technology industry and agriculture Healthcare worker Gastroenterology stomatognathic system Nasal Swab Internal medicine parasitic diseases medicine Single specimen business |
| Popis: | We prospectively compared healthcare worker-collected nasopharyngeal swabs (NPS) to self-collected anterior nasal swabs (ANS) and straight saliva for the diagnosis of COVID-19 in 354 patients. The positive percent agreement between NPS and ANS or saliva was 86.3% (95% CI: 76.7-92.9) and 93.8% (95% CI: 86.0-97.9), respectively. Negative percent agreement was 99.6% (95% CI: 98-100) for NPS vs. ANS and 97.8% (95% CI: 95.3 – 99.2) for NPS vs. saliva. NPS (n=80) and saliva (n=81) detected more cases than ANS (n=70), but no single specimen type detected all SARS-CoV2 infections. |
| Databáze: | OpenAIRE |
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