Epidemiological and clinical scenario of chronic liver diseases in Italy: Data from a multicenter nationwide survey
| Autor: | Caterina Sagnelli, Evangelista Sagnelli, Piero Luigi Almasio, Caterina Furlan, Giovanni Battista Gaeta, Sergio Babudieri, Antonina Smedile, Tommaso Stroffolini, Giuseppina Brancaccio, Nicola Coppola, Filomena Morisco |
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| Přispěvatelé: | Sagnelli, Evangelista, Stroffolini, Tommaso, Sagnelli, Caterina, Smedile, Antonina, Morisco, Filomena, Furlan, Caterina, Babudieri, Sergio, Brancaccio, Giuseppina, Coppola, Nicola, Gaeta, Giovanni Battista, Almasio, Piero Luigi, Sagnelli E., Stroffolini T., Sagnelli C., Smedile A., Morisco F., Furlan C., Babudieri S., Brancaccio G., Coppola N., Gaeta G.B., Almasio P.L. |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
Cirrhosis Alcohol abuse Gastroenterology 0302 clinical medicine Non-alcoholic Fatty Liver Disease Surveys and Questionnaires Epidemiology Outpatients 80 and over Surveys and Questionnaire Chronic hepatitis Chronic liver diseases HCC Liver cirrhosis Adolescent Adult Aged Aged 80 and over Alcoholism Carcinoma Hepatocellular Female Genotype Hepatitis B Hepatitis C Humans Inpatients Italy Liver Cirrhosis Liver Neoplasms Middle Aged Young Adult Hepatology 030212 general & internal medicine Young adult Medicine (all) Chronic liver disease virus diseases Outpatient Liver Neoplasm 030211 gastroenterology & hepatology Inpatient Human medicine.medical_specialty Liver Cirrhosi 03 medical and health sciences Internal medicine medicine business.industry Carcinoma Hepatocellular medicine.disease digestive system diseases Etiology Chronic hepatiti business |
| Popis: | The last Italian prevalence survey on chronic liver diseases (CLD) was performed in 2001. The present study evaluated the changes occurring over thirteen years. Background The last Italian prevalence survey on chronic liver diseases (CLD) was performed in 2001. The present study evaluated the changes occurring over thirteen years. Methods We enrolled 2,557 CLD consecutive patients in 16 Italian liver units in 2014. Results HBV etiology accounted for 513 (20.2%) cases, alone in 439 and associated with HCV and/or alcohol abuse in 74. Of these 513, 11.9% were anti-HDV-positive and 7.2% HBeAg-positive. HCV alone was responsible for 50.3% of CLD and with alcohol abuse for 5.9%. HCV RNA was detected in 64.0% of the anti-HCV-positive patients tested. HCV genotyping, performed for 899 patients, showed genotype-1a, 1b, 2, 3, 4 and 5 respectively in 16.5%, 45.5%, 15.4%, 8.2%, 15.1% and 0.2%. Alcohol abuse alone was responsible for 6.4% of cases and NAFLD/NASH for 6.3%. Liver cirrhosis (p |
| Databáze: | OpenAIRE |
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